Cell and gene therapy holds great promise for the treatment of cancer and a range of complex diseases. Therefore, researchers are looking for ways to improve the efficacy and safety of cell and gene therapy products, while also shortening development timelines. Traditional approaches to identifying the cells with the most efficacious characteristics for therapy development provide only estimates of function. Functional single-cell proteomics can quickly and efficiently identify superpowered single cells correlating to in vivo biology, accelerating the development of advanced therapeutics.

In this playbook from IsoPlexis, we explore how this cutting-edge technology is applied in preclinical/translational therapy development. Topics covered include:

• An overview of cell and gene therapy
• The role of functional single-cell proteomics in cell and gene therapy
• Functional single-cell proteomics as a product quality metric
• Why functional single-cell proteomics is accelerating preclinical/translational development

​