In this eBook, we explore some of the challenges encountered when imaging 3D culture models, shedding light on the latest microscopy solutions that can empower scientists to make new advances in areas such as regenerative medicine, drug discovery, and disease research.

Gain deeper, more translatable insights into organoid and spheroid models.

Organoids and spheroids are playing an increasingly vital role in drug discovery and disease research, driven by scientific innovation and regulatory shifts such as the FDA’s Modernization Act 2.0, which promotes new approach methodologies (NAMs) and non-animal technologies (NATs).

Fully harnessing the potential of these models demands specialized imaging approaches. In this new eBook, explore how advanced microscopy techniques, AI-based analysis, and streamlined workflows can help to overcome key challenges in organoid, and spheroid, imaging and unlock more translational insights.

Why Download This eBook?

• Understand how to overcome key challenges when imaging dense 3D multicellular systems
• Read real-life case studies using microscopy to shed light on drug uptake, disease modeling, tracking single cell fate in organoids and spheroids, and more
• See how advanced imaging techniques can offer different insights into lung, intestinal, endometrial, and breast cancer organoids

Case Studies Include:

• Imaging lung organoids at the “liquid-air interface” to study potential therapeutic approaches for lung disease
• Investigating the emergence and maturation of secretory cells in intestinal organoids for spatiotemporal characterization of organoid development
• Advancing uterine regeneration therapies with endometrial organoids
• Imaging anti-cancer drug uptake in spheroids

Discover tools to support every stage of your 3D imaging workflow – from monitoring organoid growth to AI-based analysis for more informed decision-making.